IL-6 is a driver of NMOSD

IL-6 is a pleiotropic cytokine produced by a variety of cell types and is involved in diverse inflammatory processes. Several functions of IL-6 are implicated in the pathogenesis of NMOSD. 2-4

BBB=blood-brain barrier; CNS=central nervous system.

ENSPRYNG is thought to inhibit IL-6 signaling that contributes to the pathogenesis of NMOSD 1

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